Mesenchymal stem cells secretions for treating neurological diseases and their mechanism of action

  • Peng Deng Shaanxi University of Chinese Medicine/Xi’an Jiaotong University
  • Xiangwen Tang Shaanxi University of Chinese Medicine/Xi’an Jiaotong University
  • Hao Yang Shaanxi University of Chinese Medicine/Xi’an Jiaotong University
Keywords: Mesenchymal Stem Cell Secretions; Neurological Diseases; Neuroinflammation; Nerve Repair


Neurological diseases are a class of diseases that seriously affect human health, including stroke, Parkinson’s disease, Alzheimer’s disease and spinal cord injury. Traditional treatments have some limitations in the treatment of these diseases, such as drug side effects, surgical risks, etc. In recent years, secretions from mesenchymal stem cells (MSCs) have attracted much attention as a new method to treat neuro_x005flogical diseases. The secretions are composed of a variety of bioactive components, which can exert their therapeutic effects by regulating the inflammatory response, promoting the regeneration and repair of nerve cells, and resisting oxidative stress. This review aims to review the application of MSC secretions in the treatment of neurological diseases and explore the mechanism of action.


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Review Article