Risk factors for ventilator-associated pneumonia in ICU me_x005fchanically ventilated patients: a meta-analysis

  • Qin Guan Dali University
  • Xiaoling Zhu Medical Department of the First Affiliated Hospital of Dali University
  • Lu Zhou Dali University
  • Zhipeng Xue Dali University
  • Binrun Zhang Medical Department of the First Affiliated Hospital of Dali University
Keywords: Mechanical Ventilation; Ventilator Associated Pneumonia; Risk Factors


Objective: This study aims to determine the risk factors for the development of ventilator-associated pneumonia (VAP) in ICU mechanically ventilated patients through meta-analysis. Method: Conduct a comprehensive search of multiple domestic and international databases, collect literature on the risk factors of VAP in ICU patients from November 2023, and conduct meta-analysis using RevMan5.4 software. Result: 31 high-quality studies were included, and it was found that age, COPD history, position, APACHE II score, antibiotic combination, repeated tracheal intubation, tracheostomy, indwelling gastric tube, mechanical ventilation time, and ICU hospitalization time were significantly associated with an increased risk of VAP; However, consciousness disorders and hypoalbuminemia do not show a signifi_x005fcant correlation with the risk of VAP. Conclusion: Specific patient characteristics and clinical procedures are associated with increased risk of VAP, and clinical attention should be paid to these risk factors in order to intervene early to prevent VAP and improve patient prognosis.


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Review Article