Effects of Ginsenosides on Cardiomyocytes and NF in Type 2 Diabetes Rats B Expression

  • Qi Geng Ginsenoside Rg1; Type 2 Diabetes Rats; Myocardial Cells; NF- κ B
Keywords: Ginsenoside Rg1; Type 2 Diabetes Rats; Myocardial Cells; NF B


Objective: To explore the clinical medicinal value of ginsenosides. Methods: 24 male type 2 diabetes rats aged 7 weeks were taken as the research object, and the myocardial cell morphology, infammatory factor content and NF in each group were observed by grouping them with diferent doses- κ B expression. Result: The swelling degree of cells in the CP Rg50 group was alleviated most signifcantly, with a signifcant reduction in deep staining of the nucleus, a signifcant reduction in cell shrinkage, and a basic trend towards normal cell morphology. Meanwhile, compared to the control group, the CP Rg50 and CP Rg25 groups showed signifcant diferences in IL-1 levels β/ IL-6, TNF- α It also signifcantly decreased horizontally (P0.05). Conclusion: Ginsenoside Rg1 has signifcant efects in the treatment of cardiomyopathy and is worth promoting in clinical practice.


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Review Article