Case Report: Pneumocystis Pneumonia Following Liver Transplantation Identified by High-Throughput Second-Generation Gene Sequencing Technology
Abstract
Pneumocystis, a fungus species, has emerged as one of the predominant infectious pathogens in immunocompromised patients, particularly in liver transplant recipients who require immunosuppressants. The pathogen colonizes the recipient’s lower respiratory tract and induces a pulmonary infection. Respiratory failure is one of the leading causes of mortality in organ transplant recipients, as the disease pro-gresses swiftly, its diagnosis is difcult, and it is simple for it to occur. This report details the case of a patient admitted to Calmette Hospital, afliated with Kunming Medical University, diagnosed with pneumocystis pulmonary infection post liver transplantation. The diagnosis and successful treatment of the patient were facilitated by high-throughput second-generation gene sequencing technology based on metagenom-ics, enlightening future clinical diagnoses and treatments.
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