COVID-19 Patients with Concurrent Acute Angle-Closure Glaucoma: A Retrospective Hospital Study.”

  • Min Zhuang The Yancheng Clinical College of Xuzhou Medical University, The Fourth Affiliated Hospital of Nantong University, The First People’s Hospital of Yancheng
  • Ying Dai
Keywords: COVID-19; Acute Angle-Closure Glaucoma; Intraocular Pressure; OCTA Imaging; Microvascular Alterations; Retrospective Study


This retrospective study investigates the interaction between COVID-19 and Acute Angle-Closure Glaucoma (AACG), analyzing clinical features, laboratory fndings, and OCTAimages in 20 patients diagnosed with both conditions. Elevated Intraocular Pressure (IOP) levels and a decrease in the deep capillary plexus (DCP) and choriocapillaris (CC) foveal vessel density were observed, with infammation and coagulation markers also elevated. These fndings suggest that the physiological changes induced by COVID-19 may exacerbate AACG symptoms. Despite the study’s limitations, including a small sample size and retrospective design, these insights are pivotal for clinicians and underline the importance of careful ocular monitoring in COVID-19 patients. Further research is warranted to explore the long-term implica-tions of these fndings and the mechanistic pathways underlying the interaction between COVID-19 andAACG.


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Review Article