Clinical Effect of Yunkang Granule Combined with Low Dose Aspirin in the Treatment of Unexplained Recurrent Abortion and Its Influence on Pregnancy Outcome

  • Yanchun Zhang Kunming Jinxin Hewanjia Obstetrics and Gynecology Hospital
Keywords: Yunkang Granule, Aspirin, Recurrent Abortion of Unknown Cause, Clinical Effect, Pregnancy Outcome

Abstract

Purpose: To study the clinical effect of Yunkang Granule combined with low dose aspirin in the treatment of unexplained recurrent abortion (URSA) and its impact on pregnancy outcome. Methods: Seventy-two patients with URSA were randomly divided into a control group and an experimental group. The control group was given conventional treatment, and the experimental group was given pregnancy-kang granules combined with low-dose aspirin. The clinical efficacy of the two treatments and their effects on hormone levels, coagulation function indexes and pregnancy outcome were compared. Results: After medication, the levels of β-HCG, P and E2 in 2 groups were higher than before medication, and the levels of β-HCG, P and E2 in observation group were higher than control group, the difference was statistically significant (P < 0.05). Compared with before medication, the levels of coagulation function indexes PT, TT and APTT were increased in both groups after medication, while the levels of FIB were decreased. The levels of coagulation function indexes PT, TT, APTT and FIB in observation group were better than those in control group after medication, and the difference was statistically significant (P < 0.05). After treatment, the total effective rate of the experimental group was significantly increased, and the pregnancy outcome was significantly improved. Conclusion: The combination of Yunkang granule and low-dose aspirin in the treatment of URSA has obvious curative effect, can significantly improve the pregnancy outcome, and is worthy of clinical promotion.

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Published
2023-06-01
Section
Original Research Article