The Value of Cefoperazone Sulbactam and Amiloride Hydrochloride in the Treatment of Chronic Obstructive Pulmonary Disease

Rong Fan, Wei Xiao, Weihua Hu, Zhu Wu


Objective: To observe the effect of different drug regimens in the treatment of chronic obstructive pulmonary disease (COPD). Methods: Sixty-two patients with COPD admitted from 2020.9 to 2022.12 were divided into two equal groups, group A and group B. Thirty-two patients each were treated with cefoperazone sulbactam, while group B was treated with ambroxol hydrochloride. Results: The total effective rate in Group B reached 93.55%, higher than 67.74% in Group A (X²=5.063, P=0.024<0.05). The time to disappearance of disease symptoms and hospital stay were shorter in Group B than in Group A. The difference reached a significant level (P < 0.05). Conclusion: Clinical treatment of COPD patients with amiloride hydrochloride combined with cefoperazone sulbactam as early as possible is effective and worth promoting.


Chronic Obstructive Pulmonary Disease; Cefoperazone Sulbactam; Ambroxol Hydrochloride; Effect Observation

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Peng GR, Wang SP. Correlation between sputum pathogenic bacteria analysis and BODE index in patients with acute exacerbation of chronic obstructive pulmonary disease[J]. Journal of Clinical Pulmonology,2021,26(09):1356-1359.

He XP. Effect of nebulized inhalation of ambroxol hydrochloride on acute exacerbation of chronic obstructive pulmonary disease[J]. China Urban and Rural Enterprise Health,2022,37(01):131-132.

Sun GH. Analysis of antimicrobial drug treatment during acute exacerbation of chronic obstructive pulmonary disease[J]. Electronic journal of clinical medicine literature,2019,6(93):63.



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