CIC Rearrangement Sarcoma: A Case Report and Literature Review

  • Haobin Chen Guangdong Provincial People's Hospital
  • Shi Cheng Guangdong Provincial People's Hospital
  • Wenhan Huang Guangdong Provincial People's Hospital
  • Yuan Yan Guangdong Provincial People's Hospital
  • Yu Zhang Guangdong Provincial People's Hospital
DOI: https://doi.org/10.18686/aem.v11i4.312
Keywords: Undifferentiated Sarcoma, CIC, Diagnosis, Differential Diagnosis, Treatment, Unplanned Surgery

Abstract

Background: CIC-rearranged sarcoma (capicua transcriptional repressor- rearranged sarcoma, CRS) is a rare type of undifferentiated small round-cell sarcoma. There are few reported cases of CRS; in 2017, 115 cases were reported abroad and 10 cases were reported in China. Case summary: The patient is a 41-year-old male who presented with a mass in the left lumbar region for more than 1 month. Tumor excision was performed at another hospital. Pathology results indicated CRS. PET-CT indicated changes in the left lumbar region, and postoperative tissue repair changes were considered. However, combined with the medical history and imaging features, the clinical diagnosis was considered recurrence of tumor in the left lumbar region. Postoperatively, the patient was transferred to the burn department for pedicled skin-flap repair. Conclusion: CRS is rare, and the prognosis of these patients is poor. Surgical resection of the lesion is the first choice for patients without metastasis.

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Published
2023-03-02
Issue
Vol 11, No 4 (2022)
Section
Original Research Article

Copyright (c) 2023 Haobin Chen

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