High Flow Nasal Catheter (HFNC) for Sepsis Induced Respiratory Failure After Extubation Meta Analysis of Clinical Control Studies on Reintubation Rate and Mortality

  • Bo Li Shaanxi Traditional Chinese Medicine Hospital
  • Xuanguo Zhang Shaanxi Traditional Chinese Medicine Hospital
  • Gaojie Wang Shaanxi Traditional Chinese Medicine Hospital
  • Qiuzhen Yuan Shaanxi Traditional Chinese Medicine Hospital
  • Minjuan Shi Shaanxi Traditional Chinese Medicine Hospital
  • Li Xi Shaanxi Traditional Chinese Medicine Hospital
DOI: https://doi.org/10.18686/aem.v12i1.304
Keywords: Sepsis, Respiratory Failure, High Flow Nasal Catheter, Noninvasive Positive Pressure Ventilation

Abstract

Objective: To analyze the reintubation rate and mortality of patients with sepsis complicated (or induced) respiratory failure after extubation, and to seek evidence-based basis for the efficacy of HFNC in the re intubation rate and mortality of sepsis induced respiratory failure after extubation. Methods: The databases of PubMed, EMBASE, Ovid, CNKI, CBM, VIP and Wanfang were searched to find the clinical studies of patients with sepsis and respiratory failure, and meta-analysis was carried out by Stata software. Results: Meta analysis showed that there was no significant difference between HFNC and noninvasive positive pressure ventilation (NPPV) in 72 hour reintubation rate, mortality during ICU and 28-day in hospital. Conclusion: The reintubation rate and mortality of HFNC after extubation in sepsis induced respiratory failure are equivalent to that of NPPV.

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Published
2023-03-21
Issue
Vol 12, No 1(2023)
Section
Original Research Article

Copyright (c) 2023 Bo Li

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