Progress of Autophagy Related Research in the Treatment of Ophthalmic Diseases

  • Zuyan Zhang Department of Ophthalmology, the Fourth Affiliated Hospital of Harbin Medical University
  • Xueqing Deng Department of Ophthalmology, the Fourth Affiliated Hospital of Harbin Medical University
  • Ying Su Department of Ophthalmology, the First Affiliated Hospital of Harbin Medical University
  • Feng Wang Department of Ophthalmology, the First Affiliated Hospital of Harbin Medical University
DOI: https://doi.org/10.18686/aem.v11i4.270
Keywords: Autophagy, Keratopathy, Retinal Diseases, RPE Degeneration, Glaucoma, RGCs Apoptosis

Abstract

Autophagy is a process in which some organelles and proteins are wrapped by cells into specific membranes and then transported to lysosomes to degrade these membranes, ultimately degrading small molecules and energy. Autophagy can make cells have a certain tolerance to starvation, and remove damaged organelles and protein structure dislocation caused by cell aging, so as to balance the intracellular environment. Autophagy includes autophagy molecules, microactive autophagy and macrophage autophagy. The mechanism characteristics of autophagy itself have aroused the upsurge of relevant application research, and more and more diseases are related to it. This paper reviews the research progress of autophagy in novel clinical application of autophagy.

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Published
2023-03-02
Issue
Vol 11, No 4 (2022)
Section
Original Research Article

Copyright (c) 2023 Zuyan Zhang

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