Research Progress of Improving MDD by Fecal Microbiota Transplantation Affecting Intestinal Microbiota-Gut- Brain Axis

  • Jixuan Liu Shenyang Pharmaceutical University Wuya College of Innovation
DOI: https://doi.org/10.18686/aem.v11i1.218
Keywords: FMT, Depression, Intestinal Flora

Abstract

It has been improved that fecal microbiota transplantation (FMT) can alleviate gastrointestinal disorders such as Clostridium difficile infection (CDI). Moreover, some studies have also concluded that FMT is available in alleviating Major Depressive Disorder (MDD), also known as depression widely, by regulating microbiota-gut-brain axis (MGBA), hence, this paper summarized the relationship between MGBA and MDD and mechanisms of MDD which is related with MGBA. And this review retrospected the animal experiments and clinical studies on the treatment of depression with FMT in recent years and discussed the future development of FMT, in order to assess whether FMT is potential and credible in the treatment of depression.

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Published
2022-03-29
Issue
Vol 11 No 1 (2022)
Section
Original Research Article

Copyright (c) 2022 Jixuan Liu

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