Research Advance about Poor Response to Anti-VEGF in Neovascular Age-Related Macular Degeneration

  • Siyuan Nie Jinan University
Keywords: Neovascular Age-Related Macular Degeneration, Poor Response, Anti-VEGF, Review

Abstract

Neovascular age-related macular degeneration (nAMD) has become one of the main causes of vision damage in middle-aged and elderly people, Now, anti-vascular endothelial growth factors (anti-VEGF) therapy has achieved a milestone in the treatment of nAMD, However, in clinical practice, the phenomenon of poor or even non-response of anti-VEGF drugs is still found, even maximal anti-VEGF treatment to some patients. The research on poor response to anti-VEGF therapy is also a hot topic in recent years. This article gives a brief review on diagnostic factors, This article gives a brief review on diagnostic factors, pathogenesis, characteristics of lesions and drug factors for the poor response of anti-VEGF drugs to nAMD.

References

[1] Song P, Du Y, Chan KY, et al.The national and subnational prevalence and burden of age-related macular degeneration in China[J].J Glob Health, 2017, 7(2):020703.

[2] De Jong PT. Age-related macular degeneration[J]. N Engl J Med, 2006, 355(14): 1474-1485.
Published
2023-06-01
Section
Original Research Article