The Effect of Obesity on Insulin Resistance in Terms of Cytokines and Hormones

  • Yutong Gao
DOI: https://doi.org/10.18686/aem.v10i2.189
Keywords: obesity, insulin resistance, cytokines, hormones

Abstract

With the increasing incidence and mortality of obesity, obesity-related health problems have become a worldwide priority. Clinical observation shows that obesity related to adipocyte differentiation is an important pathogenic factor of insulin resistance, and weight loss can reduce insulin resistance, indicating that obesity is related to insulin resistance. As the understanding of mechanism between obesity, cytokines, hormones and insulin resistance becomes clear, it is possible that these cytokines or hormones could be used in the use of biomarkers and the design of targeted therapies for insulin resistance. This review provides an overview of how obesity effect adipokines，hepatokines and inflammatory cytokines whose changes result in or exacerbate insulin resistance.

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Published
2021-08-16
Issue
Vol 10 No 2 (2021)
Section
Original Research Article

Copyright (c) 2021 Yutong Gao

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