Detection and Optimization of Cardiac Markers Based on High Sensitivity C-Reactive Protein

  • Chen Dai
Keywords: Heart Marker, High Sensitivity C-reactive Protein, Detection Method, Myocardial Infarction

Abstract

Cardiac markers play an important role in prognosis and follow-up treatment. Therefore, it is of great practical significance to study the detection methods of high-sensitivity C-reactive protein cardiac markers. The purpose of this paper is to study the optimal method for the detection of cardiac markers of high-sensitivity C-reactive protein. In this paper, the significance of cardiac markers and high-sensitivity C-reactive protein and the relationship between them and myocardial infarction were first described. The BCA method for the purification and identification of C-reactive protein was studied, and then the determination and optimization of high-sensitivity C-reactive protein and high-sensitivity C-reactive protein in healthy people were further understood. To explore the application of serum high sensitive C-reactive protein in the detection of cardiac markers in 50 patients with acute myocardial infarction and 50 healthy people. The results showed that the experimental group was (21.57 ± 1.50), (37.62 ± 1.66), (529.20 ± 5.72), (95.79 ± 6.24) ng / ml, the control group was (0.90 ± 1.10), (1.71 ± 0.14), (35.25 ± 4.21), (0.99 ± 0.71) ng / ml, and the difference between the two groups was statistically significant (P < 0.05).

References

[1] Laura CT, Eliana M, María S, et al. Detection of reactive oxygen and nitrogen species (ROS/RNS) during hypersensitive cell death. Plant Programmed Cell Death 2018; 116(6): 97-105. doi: 10.1007/978-1-4939-7668-3_9.
[2] Masayuki T. High-sensitive C-reactive protein in primary aldosteronism. Journal of Hypertension 2017; 35(1): 200. doi:10.1097/HJH.0000000000001163.
[3] Reihane J, Elham K. Level of high sensitive C-reactive protein and procalcitonin in pregnant women with mild and severe preeclampsia. Advanced Biomedical Research 2017; 6(1): 140. doi: 10.4103/2277-9175.218032.
[4] Luigi R, Nick AB, Antoine M. Ultra-high sensitive C-reactive protein during normal pregnancy and in preeclampsia: a pilot study. Journal of Hypertension 2019; 37(5): 1. doi: 10.1097/HJH.0000000000002003.
[5] L. Ziyun, L. Bo, J. Ye. Association between serum uric acid levels and high sensitive C-reactive protein in patients with type 2 diabetes. Zhonghua Yi Xue Za Zhi 2017; 97(28): 2181-2185. doi: 10.3760/cma.j.issn.0376-2491.2017.28.005.
[6] Boyapati R, Chinthalapani S, Ramisetti A, et al. Association of pentraxin and high-sensitive C-reactive protein as inflammatory biomarkers in patients with chronic periodontitis and peripheral arterial disease. Journal of Indian Society of Periodontology 2018; 22(2): 112-115.
[7] Aidin L, Behzad E. The role of supplements in reducing cardiovascular events by decrease in highly sensitive C-reactive protein and serum homocysteine. Saudi Journal of Kidney Diseases & Transplantation 2017; 28(6): 1451. doi: 10.4103/1319-2442.220853.
[8] Kaur M. C-reactive protein: A prognostic indicator. International Journal of Applied & Basic Medical Research 2017; 7(2): 83-84. doi: 10.4103/ijabmr.IJABMR_63_17.
[9] Dimitrios V, Nikolaos P, Ioanna K. C-reactive protein and frailty in the elderly: A literature review. Journal of Clinical Medicine Research 2017; 9(6): 461-465. doi: 10.14740/jocmr2959w.
[10] Sujaya G, Shaili P, Sushil K. C-reactive protein in periodontitis and its comparison with body mass index and smoking behaviour. Journal of the Nepal Medical Association 2017; 55(206): 226-233. doi: 10.31729/jnma.3134.
[11] Jonathan B, Chris TL. Heart fat in HIV: Marker or mediator of risk?. Current Opinion in Hiv & Aids 2017; 12(6): 1. doi: 10.1097/COH.0000000000000414.
[12] Moczulska B, Kubiak M, Bryczkowska A, et al. Pulse wave velocity as an early marker of diastolic heart failure in patients with hypertension. Polski Merkuriusz Lekarski Organ Polskiego 2017; 42(250): 142-144.
Published
2020-02-16
Section
Original Research Article