Clinical Study on the Aerosol Inhalation of Budesonide in Treatment of Acute Exacerbation of COPD

  • Huifeng Duan
Keywords: Budesonide, Aerosol, Acute exacerbation, COPD

Abstract

Objective: To observe the clinical effect and adverse reaction of aerosol inhalation of budesonide in treatment of acute exacerbation of COPD. 110 cases of patients with acute exacerbation of chronic obstructive pulmonary disease, who were treated in our department from January 2009 to January 2011, were selected as research objects (69 males, 41 females). All the patients were divided into control group and observation group. The two groups were treated routinely, in addition, the control group was treated with vein administration of methylprednisolone, the observation group received aerosol inhalation of budesonide, observed the clinical effect. Result: The clinical effect of observation group is better and the adverse reaction rate is clearly lower. Conclusion: Comparing with the control group which is treated with vein administration of methylprednisolone on the basis of routine treatment, the effect of observation group which is treated with aerosol inhalation of budesonide is extremely precise and its adverse reaction is also relatively less. Meanwhile, it has a higher security and its clinical effect is worth applying.

References

1.Cristina RR, Francisco JGT, Francisco JG, Jose M, Marin T. Classification of Chronic Obstructive Pulmonary Disease Severity According to the New Global Initiative for Chronic Obstructive Lung Disease 2011 Guidelines: COPD Assessment Test Versus Modified Medical Research Council Scale. Archivos de Bronconeumologia (English Edition). 2013.
2. Luo ZP, Zhou Y. clinical observation on aerosol inhalation of budesonide in treatment of Acute exacerbation of COPD. China Healthcare Innovation. 2010,5(13):22–23.
3. National Heart, Lung, and Blood Institute.Global initiative for chronic obstructive lung disease. NHLBI Workshop Report. 2003:Chapter4.
4. The chronic obstructive pulmonary disease group of Respiratory Branch of Chinese Medicine Academy. The guide on diagnosis and treatment of chronic obstructive pulmonary disease (Revised in 2007). Chinese Journal of Tuberculosis and Respiratory Diseases. 2007;30(1):8–17.
5. Wu TX. The efficacy of aerosol inhalation of budesonide in treatment of acute exacerbation of COPD. Clinical Education of General Practice. 2006;4(6):512.
6. Stanislaw D, Irena P, Aneta K, Adam Z, Wojciech B, Konrad P, Ivana S, Michal D, Anna K, Renata J, Piotr M. Met abolomics provide new insights on lung cancers tagging and discrimination from chronic obstructive pulmonary disease. Journal of Pharmaceutical and Biomedical Analysis. 2014;100.
7. Ye SL, Li CH. Clinical observation on the aerosol inhalation of budesonide in treatment of acute exacerbation of COPD.Journal of Jianghan University (Natural Science Edition). 2011;9(1):80.
8. Vera W, Christine S, Verena G, Michael S, Regina P, Claudia B, IreneJ H, Raymond V, Lena H, Steffen TS. Breathlessness, Functional Status, Distress and Palliative Care Needs Over Time in Patients with Advanced Chronic Obstructive Pulmonary Diseaseor Lung Cancer: A Cohort Study. Journal of Pain and Symptom Management. 2013.
Published
2018-03-19
Section
Clinical Therapy