Correlation Between Serum C-Reactive Protein And Cystatin C In Patients With Acute Cerebral Infarction And Carotid Artery Stenosis

  • Tao Zhang Hubei shiyan city taihe hospital(Hubei Medical College Hospital), Department of Neurosurgery, Hubei shiyan city
  • Xiaowen Yang Hubei shiyan city taihe hospital(Hubei Medical College Hospital), Inspection Medical Center, Hubei shiyan city
  • Hui Wang Hubei shiyan city taihe hospital(Hubei Medical College Hospital), Department of Neurosurgery, Hubei shiyan city
  • Jie Luo Hubei shiyan city taihe hospital(Hubei Medical College Hospital), Department of Neurosurgery, Hubei shiyan city
  • Anrong Li Hubei shiyan city taihe hospital(Hubei Medical College Hospital), Department of Neurosurgery, Hubei shiyan city
  • Yi Zhou Hubei shiyan city taihe hospital(Hubei Medical College Hospital), Department of Neurosurgery, Hubei shiyan city
  • Yusi Cheng Hubei shiyan city taihe hospital(Hubei Medical College Hospital), Department of Neurosurgery, Hubei shiyan city
DOI: https://doi.org/10.18686/aem.v7i1.124
Keywords: Acute cerebral infarction, Carotid stenosis, Serum C-reactive protein, Serum cystatin C, Correlation

Abstract

To investigate the correlation between serum C-reactive protein (CRP) and serum cystatin C (Cys-C) levels in patients with acute cerebral infarction and carotid artery stenosis. Methods: From January 2015 to December 2016 admitted to our hospital new acute cerebral infarction parallel neck vascular color Doppler ultrasound examination showed 121 cases of carotid stenosis as the case group; select the same period of hospitalized patients with non-cerebrovascular disease in 50 cases As a control group. Fasting venous blood was collected on the third day after onset of the disease and serum levels of CRP and Cys-C were measured and compared. Results: Serum levels of CRP and Cys-C in case group were significantly higher than those in control group (P <0.05). The correlation between serum CRP and Cys-C was found in any pairwise comparison (r = 0.4732). The level of CRP and Cys-C were closely related to the degree of carotid artery stenosis (P <0.05). Conclusion: The combined detection of serum CRP and Cys-C levels can be used to evaluate the degree of carotid artery stenosis in patients with acute cerebral infarction and provide a reference for the next carotid endarterectomy.

Published
2018-04-19
Issue
Vol 7 No 1 (2018)
Section
Cases Report

Copyright (c) 2018 Tao Zhang, Xiaowen Yang, Hui Wang, Jie Luo, Anrong Li, Yi Zhou, Yusi Cheng

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