Advanced Emergency Medicine

Analysis of the related factors of deep vein thrombosis after gynecological tumor surgery

Objective To investigate the risk factors of deep vein thrombosis (DVT) in patients after gynecological tumor surgery. Methods From March 2014 to March 2024, 57 patients with deep vein thrombosis after surgical treatment in the Department of Oncology and gynecology of our hospital were selected as the research sample, and were included in the observation group. In addition, 55 patients without deep vein thrombosis after gynecological tumor surgery were included in the control group. The clinical data of the patients were collected, and the related factors of postoperative deep vein thrombosis were analyzed. Results Univariate analysis showed that age, BMI, operation time, operation range, hypertension and diabetes, platelet count, benign and malignant tumor, preoperative fluid infusion were related to the occurrence of postoperative deep vein thrombosis (P < 0.05). Multiple regression analysis showed that age > 40 years, BMI>25 kg/m2, malignant tumor, hypertension and diabetes, platelet count > 300×109/L were independent risk factors for postoperative DVT, while preoperative fluid infusion was a protective factor for postoperative DVT. Conclusion Age, BMI, malignant tumor, combined cardiovascular technology and platelet count are related to the occurrence of deep vein thrombosis after gynecological tumor surgery, and no preoperative fluid infusion is a protective factor.

Research on the Application and Value of Exercise Training in Cardiac Rehabilitation

This study focuses on the application and effect evaluation of exercise training in cardiac rehabilitation. In view of the high incidence trend of cardiovascular diseases, the importance of cardiac rehabilitation in promoting patient recovery and improving quality of life has become increasingly prominent. This paper elaborates on the implementation strategies of exercise training in cardiac rehabilitation, including the formulation of personalized exercise prescriptions, safety monitoring of exercise training, and guidance and support from professionals.

Clinical Application Research of the Transradial Approach in Neurointerventional Surgery

This study aims to comprehensively investigate the clinical application and advantages of the transradial approach in neurointerventional procedures. Through in-depth analysis, it was found that the transradial approach significantly reduces the occurrence of surgical complications, improves patient comfort, and effectively shortens hospital stays, thereby lowering overall medical costs. The study content elaborates on the technical essentials and operational procedures of this approach in neurointerventional surgery, including preoperative preparation, precise puncture techniques, catheter manipulation, and other critical links.

A review of the research progress of organ chips in the field of biomedicine

Organ chips is a cutting-edge frontier science in the field of life sciences. It has broad application prospects and development space in the fields of tissue and organ development, disease mechanism research, new drug evaluation and selection, and biological research, and it has significant strategic significance for supporting the development of innovative drugs and translational medicine. This review summarizes the current research status, challenges, and application prospects of organ chips technology in the field of biomedicine both at home and abroad.

Huoxue Quscar granules combined with erbium-doped fiber laser therapeutic instrument in the treatment Clinical application of atrophic scars in acne

Objective: To compare the clinical efficacy and safety of Huoxue-Quscar granules combined with erbium-doped fiber laser therapeutic instrument and Huoxue-Quscar granules alone in the treatment of atrophic acne scars. Methods: A total of 350 patients with atrophic acne scars treated in our hospital were randomly divided into an experimental group and a control group. The patients in the experimental group were treated with Huoxue-Quscar granules combined with erbium-doped fiber laser therapeutic instrument, and the patients in the control group were treated with Huoxue-Quscar granules. The effective rate and incidence of adverse reactions were compared between the two groups. Results: The effective rate of the trial group was 97.14%, which was significantly higher than 92.00% of the control group (P < 0.05). The incidence of adverse events in the experimental group (0.57%) was lower than that in the control group (4.00%) (P < 0.05).Conclusions: Huoxue-Quscar granules combined with erbium-doped fiber laser therapeutic instrument has good efficacy and safety in the treatment of atrophic acne scars.

Clinical application analysis of neonatal swimming combined with stroking

Objective: To investigate the effects of swimming combined with touch intervention on neonatal body weight, length, psychological development, immune response and skin health, and to provide scientific basis for clinical work. Methods: In this study, 200 newborns were randomly divided into experimental group (swimming combined with touch intervention group) and control group (routine care group) using a prospective randomized controlled experiment design. The experimental group swam and touched 2-3 times a week for 4 weeks; The control group received only routine care. Before and after the intervention, weight, length, psychological development, immune response and skin health were evaluated, and SPSS 26.0 software was used for data analysis. Result: In the experimental group, newborn body weight increased by 1.53 kg (P < 0.001), body length increased by 2.6 cm (P < 0.05), psychological development score increased by 7.8 points (P < 0.001), immune response increased (antibody titer increased by 18.7, P < 0.001), skin damage rate decreased (P = 0.003). There were also significant changes in the control group. Conclusion: Swimming combined with touch intervention can significantly promote the growth and immune function of newborns, improve their skin health, contribute to psychological development, and have high clinical application value.

Comparison of the efficacy of vitrectomy combined with different filling procedures in the treatment of rhegmatogenous retinal detachment of macular detachment

Background and purpose: To compare the clinical efficacy of vitrectomy combined with silicone oil tamponade and perfluoropropane (C3F8) tamponade in the treatment of macular hole retinal detachment(MHRD).Methods: The clinical data of 55 patients with MHRD who were treated in our hospital from January 2022 to January 2023 were retrospectively analyzed,They were divided into silicone oil group (n=25) and C3F8 group (n=30) according to the surgical methos. The differences in macular hole closure, retinal detachment and replacement, vision recovery and postoperative complications between the two groups were compared.Result: Three months after surgery, there was no significant difference in the macular hole closure rate between the C3F8 group and the silicone oil group (P>0.05),There was no significant difference in retinal reattachment rate between C3F8 group and silicone oil group (P>0.05),the best corrected visual acuity after surgery was significantly improved in both the C3F8 group and the silicone oil group, and the C3F8 group was better than the silicone oil group (P<0.05),there was no significant difference in the incidence of complications between the C3F8 group and the silicone oil group (P>0.05). Conclusion: Vitrectomy combined with intraocular tamponade for MHRD can effectively reposition retina and close macular holesImprove the patient’s best corrected visual acuity, and the vision recovery in the C3F8 group was better than that in the silicone oil group.

Research on Malnutrition in AIDS Patients

Malnutrition is a major factor influencing the prognosis and quality of life of AIDS patients, and screening, assessment, diagnosis, intervention, nutrition monitoring of patients with AIDS should be done as early as possible. AIDS patients suffer from malnutrition as a result of impaired immune function brought on by the ongoing invasion of HIV, and malnutrition and impaired immune function are causal of each other, affecting each other to form a vicious circle. In order to further avoid malnutrition, slow the progression of the disease, and enhance quality of life, this article examines the primary causes of malnutrition in AIDS patients as well as the nutritional programs for various AIDS patients.

Clinical study of trastuzumab combined with chemotherapy in the treatment of HER2-positive breast cancer

Objective: To evaluate the efficacy of trastuzumab combined with chemotherapy in patients with human epidermal factor receptor 2 (HER2) positive breast cancer. Methods: A total of 88 patients with HER2 positive breast cancer treated in our hospital from 2023 to January 2024 were selected. They were divided into two groups according to the random number table method: the control group44 cases, treated with chemotherapy) and the observation group (44 cases, treated with trastuzumab combined with chemotherapy). The efficacy, incidence adverse reactions, recurrence rate, metastasis rate, tumor marker levels, T lymphocyte subsets, estrogen receptor levels, and progesterone receptor levels before and after were compared between the two groups. Results: The efficacy of the observation group was higher than that of the control group, and the recurrence and metastasis rates were (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Before treatment there were no significant differences in tumor marker levels, T lymphocyte subsets, estrogen receptor levels, and progesterone receptor levels between the two groups (P>.05). After treatment, the tumor marker levels in the observation group were lower than those in the control group, and the T lymphocyte subsets, estrogen levels, and progesterone receptor levels were higher (P<0.05). Conclusion: Trastuzumab combined with chemotherapy has a high efficacy patients with HER2 positive breast cancer.