Advanced Emergency Medicine

Mechanism of osteogenic differentiation of umbilical cord mesenchymal stem cells

Mesenchymal stem cells (MSCS) exist in a variety of tissues and have multi-lineage differentiation potential. Mesenchymal stem cells have great application prospects in the treatment of bone injury diseases. The rapid initiation and efficient induction of osteogenic signaling pathways are the key to mesenchymal stem cell-based bone tissue engineering technology. Multiple signaling pathways have been confirmed to play a regulatory role in the process of osteogenic differentiation of mesenchymal stem cells. This article reviews the research progress of the mechanism of osteogenic differentiation of mesenchymal stem cells.

Application of interactive nursing in colostomy nursing of colon cancer patients

Objective: To analyze the application of interactive nursing in colostomy nursing of colon cancer patients Methods: From January 2022 to January 2023, 60 hospitalized patients with colon cancer were selected as participants in this study, and were evenly assigned to the observation group and the control group by random number table method, with 30 patients in each group. The control group was treated with routine nursing, the observation group was treated with interactive nursing, and the nursing effect was compared.Results: After treatment, it was found that the ESCA and GSES scores of the observation group were better than those of the control group, while the anxiety and depression scores of the observation group were lower than those of the control group, P<0.05, and the difference was statistically significant. Conclusion: Interactive nursing for colostomy nursing can effectively improve the nursing effect, and it is worth promoting.

Rapid Recognition and Management of Critical Illnesses in Emergency Medicine

As an important part of clinical medicine, emergency medicine bears the important responsibility of rapid identification and effective treatment of patients with acute and critical illnesses. The purpose of this paper is to discuss the rapid identification of critical illnesses in emergency medicine and its treatment strategy, through the analysis of vital signs monitoring, identification of acute and critical symptoms, first aid skills and operation standards, etc., to provide emergency physicians with a set of scientific and systematic response program, with a view to improving the efficiency of emergency treatment and patient survival rate.

Radiologic Diagnosis and Differential Diagnosis of Traumatic Fractures

This study aims to evaluate the effectiveness of radiologic methods such as X-ray, CT, and MRI in the diagnosis of traumatic fractures by detailed analysis. The diagnostic performance of these methods is assessed, and the accuracy of differential diagnosis with similar conditions is explored. By providing specific data and case examples, we hope to offer more detailed and accurate guidance for the radiologic diagnosis and differential diagnosis of traumatic fractures, ultimately enabling more precise treatment plans for patients.

Study on the effect of different doses of Ermiaosan on inflammatory response in CIA model rats

Objective: To investigate the effect of different doses of Ermiaosan on improving the inflammatory response in collagen-induced arthritis (CIA) model rats. Methods: The CIA rat model was established and randomly divided into the model group (CIA group), and low, medium, and high dose Ermiaosan groups. Each group was treated with the corresponding drugs, while the healthy control group and the model group were given an equal volume of saline by gavage. The expression of inflammatory factors IL-1β, IL-6, and TNF-α in each group was detected using ELISA, and the pathological changes in rat joints were observed using Masson staining. Results: Rats in the CIA group showed significant tissue damage, tissue proliferation, and inflammatory infiltration in the joints. The low, medium, and high dose Ermiaosan groups exhibited reduced joint tissue destruction and proliferation. Different doses of Ermiaosan were able to alleviate joint lesions in CIA rats. The expression levels of IL-1β, IL-6, and TNF-α in serum were significantly reduced in all dose groups (P<0.05). Compared with the CIA group, the medium and high dose groups showed consistent therapeutic effects, both significantly better than the low dose group. Conclusion: The medium dose of Ermiaosan achieved satisfactory therapeutic effects on the inflammatory response in CIA model rats. Ermiaosan may exert its therapeutic effects on RA by inhibiting inflammatory factors.

The value of CRP and NLR in differential diagnosis of benign and malignant pulmonary nodules

Objective: Evaluate CRP and NLR levels in benign vs. malignant pulmonary nodules for differential diagnosis. Methods: Selected 60 patients with benign nodules and 60 with lung cancer from a Hunan hospital from August 2022 to December 2023. Analyzed CRP and NLR diagnostic value. Results: Significant differences in CRP, NLR levels between groups (P<0.05). Conclusion: CRP and NLR levels are higher in lung cancer patients, indicating diagnostic value in distinguishing benign vs. malignant nodules.

Application Comparison of Different Tip Positions of Midline Catheters in Neurosurgical Patients

Objective To compare the clinical effect of midline catheter tip in different locations. Methods The 205 patients admitted to the neurosurgery department were divided into 105 patients in the catheter of the test group and 100 patients in the control group,the catheter tip of the test group located in the subclavian vein and the catheter tip of the control group in the axillary vein of the chest. Results There was no statistical difference in the catheter retention time and complications and the control group (P> 0.05). Conclusion The tip of the midline catheter is located in the subclavian vein and the axillary vein of the chest.