Cellular and Molecular Mechanisms of Hepatic Fibrosis

  • Minling Cao
  • Xiaoling Chi
  • Junmin Jiang
  • Guangjun Tian
DOI: https://doi.org/10.18686/aem.v4i3.4
Keywords: Hepatic fibrosis, Hepatic stellate cells, Mechanism

Abstract

The occurrence of hepatic fibrosis is a multi-factor involved process. The key is the activation of hepatic stellate cells (HSC). Synthesis of extracellular matrix in the liver cells increases while degradation decreases. This paper reviews the tissue factors and the mechanism closely related to the forming of hepatic fibrosis.

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Published
2015-09-18
Issue
Vol 4 No 3 (2015)
Section
Original Research Article

Copyright (c) 2015 Minling Cao, Xiaoling Chi, Junmin Jiang, Guangjun Tian

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