Risk Factors for Artificial Kidney Failure During Continuous Renal Replacement Therapy

Wen Guo, Xuemei Chen


Objective To explore the influencing factors of artificial kidney failure (AKF) during continuous renal replacement therapy (CRRT). Methods We conducted a retrospective observational study on 70 patients undergoing 199740 minutes of CRRT comprising 143 circuits at the Department of Intensive Care Medicine of First Affiliated Hospital of Chongqing Medical University from August 2021 to August 2022. Results The occurrence rate and total time of access outflow dysfunction (AOD) in AKF group increased significantly than those in nAKF group. Receiver Operating Characteristic (ROC) Curve analysis showed the optimal cutoff value of AOD total time (AODTT) was 7 minutes. Logistic regression analysis further showed that AODTT≥7 min was an independent predictor of AKF. Conclusion The presence of AOD was related to AKF. AODTT≥7 min during CRRT was an independent risk factor for AKF.


Continuous Renal Replacement Therapy; Artificial Kidney Failure; Access Outflow Dysfunction

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DOI: http://dx.doi.org/10.18686/aem.v12i2.377


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